ABSTRACT
Primary amenorrhea is one of the most important complaint of women in reproductive age. To determine the causes responsible for primary amenorrhea this study was performed on the basis of clinical, sonography and laboratories investigations. This case series study was performed at Ayat-allah Taleghani teaching hospital during the years of 2003-5. Data were collected from the patients who attended or referred to the clinics of gynecology or endocrinology wards since 10 years ago. 53 cases were evaluated. Mean age of the patients was 26.82 +/- 7.24 years when they were visited at the clinics. The most common cause of primary infertility was mullerian dysgenesis [n=19] according to clinical, sonography and laboratories investigations. Hypogonadotropic hypogonadism and congenital adrenal hyperplasia were seen in 12 and 8 patients, respectively. 5 patients had gonadal dysgenesis. This study suggest that registration of patients with primary amenorrhea in research center, can be beneficial for diagnosis and intervention